Marble Burying Test Rats

Millan m j et al stereospecific blockade of marble burying behaviour in mice by.

Marble burying test rats.

Create a clean and professional home studio setup. Burrows escape tunnels and in standard cage bedding and the nestlet shred test capitalizes on the fact that mice are nesting animals by nature that build nests for protection of themselves and their offspring against environmental conditions e. Table 3 marble burying behavior in a two compartment box no. In the marble burying test in rats it.

In comparison wky males but not females exhibited enhanced novelty induced hypophagia indicative of increased anxiety like behaviour compared to sd rats. An increasing number of investigators utilize the marble burying assay despite the paucity of information available regarding what underlies the behavior. The marble burying test is a useful model of neophobia 12 anxiety and obsessive compulsive behaviour. It is based on the observation that rats and mice will bury either harmful or harmless objects in their bedding.

The marble burying test takes advantage of the proclivity of mice to dig in natural settings e g. It has also been proposed that the test may have predictive validity. Behav brain res 2007. Since findings reported in the literature indicate that marble burying behavior.

Zimeldine 10 0 mg kg reduced marble burying without affecting locomotor activity. Of duration of marbles buried test s mean sem time of nonmarble side s mean sem time nonmarble side 300 600 1800 4 2 2 0 7 3 0 9 8 4 0 4 143 4 292 30 916 45 47 ns 49 ns 51 ns data from 10 female. While widely used there is significant controversy over the interpretation of its results. This behavior belongs is probably a type of defensive burying typical of rodents 13.

Marble burying is an animal model used in scientific research to depict anxiety or obsessive compulsive disorder ocd behavior. In the marble burying test wky females but not males exhibited a trend towards increased burying indicative of anxiety like neophobic behaviour. Probe burying test in rats. The marble burying test is a useful model of both obsessive compulsive like ocd behavior and or anxiety like behavior.

We tested the possibility that a genetic component underlies marble burying in mice and if there is a genetic correlation with other anxiety like traits. Marble burying the marble burying test is a useful model of neophobia 1 anxiety 1 7 and obsessive compulsive behavior 8 11.